Cabozantinib S-Malate- Wuhan pharmaceutical peptide Technology Co.,Ltd

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Cabozantinib S-Malate

Purchase Qty: 1
Unit: g(s)
Fob Unit Price: US $18
Production Capacity:kg
Payment Terms:PayPal

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Wuhan pharmaceutical peptide Technology Co.,Ltd

Business Type:Manufacturer

Country/Region:China

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HOT Rank

6/10

Product Information

Chemical Formula:C32H30FN3O10
Molecular Weight:635.59300
Assay:99.5%
Pharmacopeia:CP
Package Type:g/10g/100g/1kg
Shelf Life:18 months
Storage:Sealed
Place of Origin:Wuhan China

Description

Cabozantinib is a small molecule C-Met modulator. Cabozantinib acts as a potent multitargeted VEGFR2, Met, FLT3, Tie2, Kit and Ret inhibitor with IC50 of 0.035, 1.8, 14.4, 14.3 and 4.6 nM for VEGFR2, Met, FLT3, Tie2 and Kit, respectively. Cabozantinib shows dose-dependent inhibition of tumor growth and tumor regression, associated with disruption of the tumor vasculature and extensive tumor cell apoptosis